[Biotech&Pharma] Annovis Bio Announces Update on Phase II Clinical Trial for Alzheimer's Disease

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BERWYN, Pa., Feb. 13, 2020 (GLOBE NEWSWIRE) — Annovis Bio Inc. (NYSE:ANVS), a clinical-stage drug platform company addressing Alzheimer's, Parkinson's and other neurodegenerative diseases, announced today that the Data Safety Monitoring Board has reviewed the safety data, enrollment, participant status, demographic data and vital signs of patients enrolled in their Phase II clinical trial for the treatment of Alzheimer's disease and unanimously supported that the study, which is named DISCOVER, continue without modification.

The clinical trial taking place at six sites, including the University of California, San Diego, Johns Hopkins, Indiana University, Washington University, the Cleveland Clinic and Columbia University, is a 24-patient study. To date, 11 patients have been enrolled. No adverse effects have been reported in any of the enrolled patients. The clinical trial is expected to conclude in the spring of 2021 with interim data expected later in 2020.

The clinical trial was designed to test the effects of ANVS401, the Company's lead compound, on neurotoxic proteins in human spinal fluid by stable isotope labeling kinetics (SILK) for the treatment of Alzheimer's disease.

Howard Feldman, MD, Director of the Alzheimer's Disease Cooperative Study (ADCS), and Martin Farlow, MD, Professor and Vice Chairman of Research, Indiana University School of Medicine, are serving as Project Directors for the study. Funding for this research came through the National Institute on Aging ADCS grant.

This study is breaking new ground in the Alzheimer's field. It combines state-of-the-art SILK to evaluate the effects …

Full story available on Benzinga.com

Source Benzinga

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